pH gradient buffer suitable for antibody pharmaceutical analysis
A fast and reproducible pH gradient is possible! The development of the analytical method is also simple and easy.
The "pH Gradient Buffer" enables the development of analytical methods for charge variants contained in proteins and monoclonal antibodies (MAbs) through LC, as well as reducing the time required for method transfer to QA/QC. Thanks to the characteristics of the buffer components, a fast and reproducible pH gradient is achievable. Additionally, the development of analytical methods is simple and easy. Furthermore, it can be used with LC columns and systems commonly used for biomolecular analysis, and there is no time-consuming preparation of the mobile phase as with gradients using salts. 【Features】 ■ Achieves a fast and reproducible pH gradient due to the characteristics of the buffer components ■ Development of analytical methods is simple and easy ■ Usable with LC columns and systems commonly used for biomolecular analysis ■ No time-consuming preparation of the mobile phase as with gradients using salts ■ Methods using pH gradients are applicable to most MAbs
